Long Read Support

The Long Read Support plugin provides a range of tools for working with long, next-generation sequencing reads, such as those produced by Pacific Biosciences or Oxford Nanopore Technologies sequencing platforms. Specifically, this plugin provides functionality for:

• Correcting errors in long reads
• De novo assembly of long reads
• Mapping long reads against a reference
• Polishing contigs with high-quality reads
• RNA-Seq analysis of long reads
• Detection of structural variants from long reads
• Hybrid assembly of long and short reads

The tools delivered by this plugin utilize the open-source software components minimap2 and racon.

Results can be further processed by other tools of the QIAGEN CLC Genomics Workbench, QIAGEN CLC Genomics Server and relevant plugins. For example, the initial contigs obtained by assembling long reads may be further refined using tools delivered by the QIAGEN CLC Genome Finishing Module.

Figure 1. Screenshot of the tools added to the toolbox after installation of the plugin.

Latest improvements

We frequently release updates and improvements such as bug fixes or new features. To get a complete overview, please visit the latest improvements page.